Count to 10 - Anaesthetic Primary Podcast

EP42 – Live Practice Viva with Derek and Special Guest Celia | CT10

Sep 21, 2025
A live practice session unravels complex medical topics. Isomers are defined, with warfarin's potent enantiomers highlighted. Respiratory changes during pregnancy take center stage, detailing vital gas exchange factors. Mechanisms behind nausea and the role of the chemoreceptor trigger zone are explored, alongside effective antiemetics. The discussion on atelectasis emphasizes prevention techniques, the importance of PEEP, and recruitment maneuvers. Feedback offers insights into exam performance, ensuring candidates are well-prepared.
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ADVICE

Open With A Clear Definition

  • Use a clear definition first, then classify to structure your viva answer quickly.
  • Ask the examiner how far to go if details might be excessive for the opening question.
INSIGHT

Stereochemistry Alters Drug Potency

  • S‑ and R‑warfarin differ in potency because stereochemistry alters enzyme affinity.
  • S‑warfarin has greater anticoagulant activity due to higher affinity for vitamin K epoxide reductase.
ADVICE

Tailor And Monitor Warfarin Carefully

  • Monitor warfarin with INR and adjust dose for liver function, drug interactions and diet.
  • Reverse with vitamin K or replace factors using FFP or prothrombin complex concentrate if needed.
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