AI-powered
podcast player
Listen to all your favourite podcasts with AI-powered features
Critical Care Reviews Podcast
COCA Trial Panel Discussion
Dec 6, 2021
Theresa Olasveengen, Victoria Cornelius, and Christopher Seymour join trialists Mikael Fink Vallentin and Lars Andersen, as well as editorialist Gavin Perkins, to discuss the COCA trial. They explore the stone heart phenomenon, the use of dual analytic approaches in trials, and reflections on trial design and execution.
36:42
Episode guests
AI Summary
AI Chapters
Episode notes
Podcast summary created with Snipd AI
Quick takeaways
- The COCA trial experienced unusual decisions from the Data Monitoring Committee, including increasing the sample size and terminating the trial due to a signal of harm.
- Setting predefined statistical criteria for stopping a trial due to harm is challenging, and more research is needed to explore subgroups and potential mechanisms for harm in administering calcium during cardiac arrest.
Deep dives
Impressed by the trial team's bravery and execution
The speaker commends the trial team for their bravery in taking on a difficult trial and executing it well.
Get the Snipd
podcast app
Unlock the knowledge in podcasts with the podcast player of the future.
AI-powered
Discover
highlights
Listen to the best highlights from the podcasts you love and dive into the full episode
Save any
moment
Hear something you like? Tap your headphones to save it with AI-generated key takeaways
Share
& Export
Send highlights to Twitter, WhatsApp or export them to Notion, Readwise & more
AI-powered
podcast player
Listen to all your favourite podcasts with AI-powered features
Discover
highlights
Listen to the best highlights from the podcasts you love and dive into the full episode