Save My Thyroid: Healing Tips for Hyperthyroidism and Hashimoto's

Can Hyperthyroidism Cause Liver Dysfunction?

Feb 20, 2025

Untreated hyperthyroidism can significantly impact liver function, with biochemical abnormalities seen in many patients. The podcast discusses how elevated thyroid hormones lead to liver enzyme irregularities. It highlights the importance of monitoring liver health alongside thyroid issues. Listeners learn about the causes of liver dysfunction, the effect of antithyroid medications, and the links between liver concerns and heart failure. Additionally, the conversation touches on autoimmune conditions that also influence liver stability.

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Quick takeaways

Untreated hyperthyroidism can lead to significant liver dysfunction, with elevated liver enzymes seen in 15-76% of patients.

The initiation of antithyroid medications can normalize liver enzyme levels, although careful monitoring is necessary due to potential side effects.

Deep dives

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The Impact of Hyperthyroidism on Liver Function

12min

Liver biochemical abnormalities are seen in 15-76% of patients with untreated thyrotoxicosis - that is, those not taking antithyroid medication. This liver dysfunction is typically related to direct injury to the liver, comorbid heart failure, and associated autoimmune conditions. The good news is that, in most cases, liver enzymes can return to normal without lasting damage to the liver.

Today, I’m exploring what the research shows about liver dysfunction in those with hyperthyroidism. I’m talking about the relationship between untreated hyperthyroidism and liver enzyme abnormalities, potential causes, and the importance of monitoring liver function in hyperthyroid patients.

In this episode, you’ll learn about:
- Causes of liver dysfunction in those with hyperthyroidism
- How antithyroid medications can affect liver enzymes
- Specific liver enzymes impacted by untreated hyperthyroidism
- The relationship between elevated alkaline phosphatase and bone density concerns
- The correlation between heart failure and more severe liver dysfunction
- Autoimmune conditions that can impact liver health

As always, I hope you find this episode valuable, and I look forward to catching you in the next episode!

To learn more, visit the show notes at https://savemythyroid.com/podcast/can-hyperthyroidism-cause-liver-dysfunction/.

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