Good Disruption Good Disruption: Episode 26 - GLP-1 Medications for Weight Loss
Sep 1, 2025
In this engaging discussion, Dr. Sandhya Chhabra, a physician and senior medical advisor, delves into the rising trend of GLP-1 medications for weight loss. The conversation examines the societal implications and health perceptions surrounding these drugs, initially designed for diabetes management. Dr. Chhabra addresses the risks and benefits of GLP-1s, including potential side effects and the long-term effects on health. Insights into accessibility, economic factors, and their impact on the fitness industry make for a thought-provoking listen.
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Origin And Mechanism Of GLP-1s
- GLP-1s were developed for type 2 diabetes and later shown to reduce appetite by slowing gastric emptying.
- Their wider use for weight loss emerged because diabetes and obesity are closely linked biologically.
Rapid Uptake Signals Disruption
- Use of GLP-1s has jumped rapidly from single-digit to double-digit percentages of adults.
- High demand signals a broad disruptive effect across health and consumer markets.
Anticipate Appetite Suppression Effects
- Expect GLP-1s to slow digestion and increase satiety, reducing caloric intake.
- Monitor dosing and effects because appetite suppression is a primary pathway for weight loss.