

Episode 412: Metformin and the MeMeMe Study: Is It Time?
Feb 11, 2025
Explore the promising role of metformin in cancer prevention and diabetes management, highlighted by recent studies including the intriguing MeMeMe trial. Discover how statins may cut dementia risk, and learn about omega-3s' impact on aging. The podcast also dives into the hidden dangers of juicing, microplastics affecting brain health, and the importance of menopause for artery health. Plus, hear about luteolin's surprising benefits for dark hair, and the advantages of telemedicine for heart patients with diabetes.
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Statin Use Guidelines
- Dr. Kahn recommends statins only when necessary, such as for high calcium scores or abnormal coronary CT angiograms.
- He prefers low-dose statins combined with ezetimibe to minimize side effects.
Statins and Dementia Risk
- A meta-analysis of 7 million patients found statin use reduced dementia risk by 14% overall.
- Rosuvastatin performed best, reducing all-cause dementia by 28%.
Omega-3s, Aging, and Exercise
- Omega-3 supplementation slowed aging clocks in a study of older adults.
- Combining omega-3s with vitamin D and exercise provided the best results.