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Heart Doc VIP with Dr. Joel Kahn

Episode 412: Metformin and the MeMeMe Study: Is It Time?

Feb 11, 2025
Explore the promising role of metformin in cancer prevention and diabetes management, highlighted by recent studies including the intriguing MeMeMe trial. Discover how statins may cut dementia risk, and learn about omega-3s' impact on aging. The podcast also dives into the hidden dangers of juicing, microplastics affecting brain health, and the importance of menopause for artery health. Plus, hear about luteolin's surprising benefits for dark hair, and the advantages of telemedicine for heart patients with diabetes.
27:00

Podcast summary created with Snipd AI

Quick takeaways

  • Metformin shows promise not only for diabetes management but also in reducing cancer risk and promoting longevity, especially when combined with a Mediterranean diet.
  • Recent studies reveal that statins, particularly rosuvastatin, significantly lower dementia risk, highlighting their potential benefits beyond cholesterol management.

Deep dives

Statins and Dementia Risk

Statins have been shown to reduce dementia risk according to a comprehensive study involving 7 million patients. The analysis revealed that statin use lowered the risk of developing any form of dementia by 14%, with varying reductions in specific types such as Alzheimer’s and vascular dementia. Specifically, rosuvastatin demonstrated a notable 28% decrease in all-cause dementia risk. Additionally, prolonged use of statins, particularly over three years, correlated with an astonishing 63% reduction in dementia risk, challenging the common fear surrounding their usage.

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