TED Health

The surprising cause of stomach ulcers with Rusha Modi

Oct 28, 2025
Rusha Modi, the creator of a compelling TEDx lesson, dives into the groundbreaking discovery that H. pylori causes stomach ulcers. She debunks common myths about ulcers, explaining that they aren’t caused by stress or spicy food. The discussion highlights Dr. Barry Marshall’s daring self-experiment to show the connection between the bacterium and gastritis. Modi also sheds light on how our stomach protects itself and how antibiotics revolutionized ulcer treatments. This eye-opening exploration makes you rethink everything you thought you knew about ulcers!
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ANECDOTE

Doctor Who Ingested Bacteria To Prove A Point

  • In 1984 Dr. Barry Marshall swallowed a broth of bacteria from a patient's stomach to test his hypothesis.
  • He developed gastritis and later cured himself with antibiotics, proving a bacterial cause for ulcers.
INSIGHT

Common Ulcer Beliefs Were Largely Wrong

  • For decades doctors blamed stress, spicy food, or excess acid for ulcers without convincing evidence.
  • Only a tiny fraction of ulcers are caused by excess acid; most traced to other causes like infection.
INSIGHT

H. pylori Is An Ancient, Acid-Resistant Companion

  • Helicobacter pylori is an ancient, common bacterium found in about half of people worldwide.
  • H. pylori survives stomach acid using urease and many virulence proteins that disrupt mucosal defense.
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