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Future Tense

Frozen frogs, tissues and cells — the health and environmental benefits of keeping it chill

Oct 24, 2024
Join Ken Storey, a Biology Professor, alongside experts Saffron Bryant, Marlys Houck, and Justine O’Brien as they dive into the astonishing world of cryopreservation. Discover how the incredible wood frog’s ability to freeze and survive inspires advancements in organ preservation. They discuss the Frozen Zoo’s role in conserving genetic diversity across species and the unique challenges of preserving different animal cells. Plus, explore the promising potential of biobanks in restoring coral ecosystems and safeguarding biodiversity for the future.
29:08

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Quick takeaways

  • The unique cryoprotective abilities of wood frogs may revolutionize organ preservation methods, potentially reducing transplant waiting lists.
  • The Frozen Zoo plays a critical role in conserving biodiversity by preserving genetic materials, aiding efforts to recover extinct or endangered species.

Deep dives

The Marvels of Wood Frogs

Wood frogs, particularly Rana sylvatica, possess the unique ability to survive extreme cold by turning themselves into ice. At temperatures below zero, these frogs utilize nucleating proteins that initiate ice formation on their skin, which then spreads internally through their veins and arteries. This process allows for the preservation of their body while still maintaining a low level of metabolism, enabling them to effectively endure winter without completely shutting down. The frogs also produce large amounts of glucose, which works as a cryoprotectant, cushioning their cells against damage typically caused by freezing.

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