The Curbsiders Internal Medicine Podcast

#399 Wisely Ordering Autoantibodies - ACP IM2023

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Jun 12, 2023
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ANECDOTE

Early Arthritis Case Anecdote

  • A patient with joint pain and morning stiffness, without obvious synovitis, may have fibromyalgia or early autoimmune disease.
  • Follow-up and repeated assessment are crucial to catch evolving inflammatory arthritis over time.
ADVICE

Assessing Synovitis and Stiffness

  • Learn to recognize synovitis by repeated exam focusing on swelling, tenderness, and bogginess of the joint.
  • Morning stiffness lasting over 30 minutes can suggest inflammatory arthritis but may overlap with fibromyalgia.
ADVICE

Initial Lab Approach to RA

  • Initial labs for suspected rheumatoid arthritis should include ESR, CRP, rheumatoid factor, and anti-CCP.
  • Consider CBC and urine protein-creatinine ratio if clinical suspicion of systemic involvement exists.
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