LONGEVITY with Nathalie Niddam #361 How MitoQ Targets Mitochondrial Decline to Improve Energy, Vascular Health, and Aging With Siobhan Mitchell
Aug 15, 2025
In this engaging conversation with Siobhan Mitchell, a neuroscientist and longevity researcher at MitoQ, listeners discover the pivotal role mitochondria play in aging and brain health. Siobhan shares her personal journey inspired by her grandmother's Alzheimer's struggle. She explains how MitoQ supports mitochondrial function, its unique benefits over CoQ10, and its implications for vascular health and cognitive decline. The discussion also touches on the effects of environmental toxins and the importance of mitochondrial health in women's wellness and fertility.
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Personal Mission From Childhood Loss
- Siobhan Mitchell watched her grandmother decline from Alzheimer's after age eight and vowed to prevent brain aging.
- That childhood experience drove her career focus on brain health and mitochondria.
Mitochondrial Decline Starts Young
- Mitochondrial decline begins in your 20s and drives early decreases in VO2 max and reaction time.
- Targeting mitochondria can therefore affect muscles, brain, heart and skin aging systemically.
Engineered Mitochondrial Targeting
- MitoQ is an engineered compound that attaches a triphenylphosphonium tag to a CoQ-like molecule to force mitochondrial uptake.
- That tag drives dramatically higher mitochondrial delivery than standard CoQ10 formulations.