Testosterone and Sexual Desire in Postmenopausal Women

Testosterone levels naturally decline in women as they age, particularly post-menopause, contributing to a decrease in libido. Research indicates that while testosterone replacement therapy can increase sexual desire in postmenopausal women, it does not significantly affect overall mood or other health-related symptoms. A review of randomized control trials involving thousands of women found that testosterone treatment led to only a slight increase in satisfactory sexual events, raising concerns about its clinical significance. Additionally, testosterone usage in women lacks FDA approval, reflecting uncertainties regarding its long-term safety and potential side effects.