Nature Podcast

Audio long-read: The secret lives of cells — as never seen before

Dec 31, 2021
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ANECDOTE

Kukulski's Cryo-ET fascination

  • Bio-chemist Wanda Kukulski was captivated by videos of cell interiors made using cryo-electron tomography (cryo-ET).
  • She likened the experience to watching a documentary, highlighting the technique's visual appeal.
INSIGHT

Cryo-ET's Holistic View

  • Newer imaging techniques like cryo-ET allow scientists to observe biological molecules within their natural environment.
  • This holistic view reveals molecular interactions and cellular landscapes, unlike older methods.
ANECDOTE

Villa's Paparazzi Moment

  • Biophysicist Elizabeth Villa recalls her excitement at seeing cell structures with cryo-ET.
  • She felt like a "paparazzi" with unprecedented access, emphasizing the technique's revelatory power.
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