Criopib milling allows researchers to slice cells thinly before placing them under an elec microscope. Baumeister and his colleagues used this mash up of methods to visualize how molecules were arranged in the vicinity of the nucleus in a human cell. Their work revealed how nanometer thin filaments provided structural support to the nucleus, making it one of the stiffest organels in animal cells.
Cutting-edge microscopy techniques are letting researchers visualize biological molecules within cells, rather than studying them in isolation. This approach is providing new insights into how these structures interact in this complex environment.This is an audio version of our feature: The secret lives of cells — as never seen before
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