This Week in Virology TWiV 1219: Koalas sweep horse shift
May 18, 2025
The hosts tackle the pause on the chikungunya vaccine and changing COVID recommendations for vulnerable populations. They dive into the evolution of viruses, exploring receptor interactions and the fascinating world of koala retroviruses. Unique insights into the microbial makeup of belly buttons and the protective role of skin bacteria against UV radiation add a quirky touch. The discussion also reflects on the urgent need to rebuild public trust in vaccines amid misinformation and highlights the importance of effective science communication.
AI Snips
Chapters
Transcript
Episode notes
Chikungunya Vaccine Pause Insight
- The FDA paused the chikungunya vaccine for people 60+ due to some serious adverse events, including two deaths.
- Post-marketing safety monitoring is crucial as some rare adverse effects only appear after widespread vaccination.
COVID Vaccine Recommendation Change
- HHS plans to stop recommending COVID vaccines for children and pregnant people without clear rationale.
- This decision could undermine protection for vulnerable populations and possibly erode public trust.
Viral Receptor Shifts Explained
- Shifts in receptor recognition by encephalitic alphaviruses are due to just one to three amino acid changes.
- Understanding these molecular shifts helps explain viral host range and emergence patterns.