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TWiV 1219: Koalas sweep horse shift

This Week in Virology

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Viral Receptor Interactions and Evolutionary Dynamics

This chapter explores the complex interactions between viruses and host receptors, focusing on the binding of viruses to the human PCDH10 receptor and how this influences infection dynamics. It highlights significant mutations in viral proteins that affect receptor recognition, showcasing the evolutionary adaptations of viruses to different hosts, including humans and birds. Additionally, it discusses predictive modeling and therapeutic implications surrounding receptor interactions, emphasizing the importance of ongoing surveillance for emerging viral threats.

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