The Hamilton Morris Podcast

LSD and the Head Twitch Response

Dec 2, 2021

01:09:29

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Episode notes

Introduction

2min

The Effects of LSD on Permanent Behavior in Mice

4min

The Head Twitch Response to Psychedelic Drugs

3min

The Permanency of the Indole Effect

2min

The Importance of Head Twist in Psychedelics

4min

The Variability of Indol and LSD

2min

The Effects of Repeated LSD Administration on Schizophrenia

3min

The Relationship Between Psychedelics and the Head Switch

3min

The Predictive Validity of Psychedelic Effects

5min

10.

Psychedelics: A Better Model for Drug Discovery

3min

11.

The Psychological Effects of Ketamine on Depression

4min

12.

The Psychological Basis of Depression in Humans

2min

13.

The Effects of Psychedelics on Animal Behavior

2min

14.

The Importance of Psychedelics

2min

15.

The History of the HDR

3min

16.

The Effects of Cannabis on the Head to Which Response to Psychedelics

5min

17.

The Effects of Psychedelics on Head Switches

5min

18.

The False Positives of Psychedelic Drugs for HDR

3min

19.

The Potency of the Head Switch in Drug Discrimination

3min

20.

The Potential Off Negative Effects of Lysiride

2min

21.

The Importance of Experiential Experience in Anti-America Differences

2min

22.

The Psychedelic Effects of Melatonin

2min

23.

How to Explain the SAR Psychedelics

2min

24.

The Psychedelic Effects of Gufoten

2min

25.

The Implications of Capital for Pharmacological Relevance

2min

In this episode Jason Wallach and I discuss the strange origin of the head twitch response and how it became the most important behavioral correlate for 5HT2A agonism in non-human animals.

Paper: Permanent alteration of behavior in mice by chemical and psychological means

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