Degrees of Health Dr Mark Tarnopolsky, MD, PhD | Mitochondrial Mastery: Supplements, Exercise & Longevity Insights
Jan 22, 2025
Dr. Mark Tarnopolsky, a leading expert in mitochondrial health at McMaster University, dives deep into the intricate world of mitochondria. He explains their pivotal role in energy production and longevity while dissecting the impact of aging on muscle function. The discussion covers the benefits of endurance vs. resistance training for mitochondrial health and demystifies popular supplements like CoQ10 and urolithin A. Mark shares his personal fitness regimen that keeps his VO2 max impressively high, reminding listeners that there are no shortcuts to optimal mitochondrial function.
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Mitochondria's Role in Energy and Aging
- Mitochondria are the engines extracting energy and detoxifying oxygen in our cells.
- Dysfunction leads to reduced energy, muscle loss, and is linked to aging effects like sarcopenia.
Exercise Doubles Mitochondria Mass
- Exercise is the main stimulus for increasing mitochondrial mass.
- Sedentary muscles have about 2% mitochondria, which can double with training in 3 months.
Genetic Mitochondrial Disease Lessons
- Genetic mitochondrial diseases cause severe dysfunction and premature aging symptoms.
- Mild forms show cataracts, muscle weakness, illustrating mitochondria's vital role.