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Bryan Johnson's $25,000 Follistatin Gene Therapy - Dissecting The Results

Jan 1, 2025
Bryan Johnson, an entrepreneur and investor renowned for his biohacking pursuits, discusses his innovative experiments with follistatin gene therapy. He reveals insights on its potential for muscle growth and critiques its effectiveness versus social media hype. Johnson reviews a recent study examining stable health markers and highlights the complexities of isolating therapy effects. The conversation also confronts exaggerated claims about biological age reduction, emphasizing the need for rigorous research and a consensus in the medical community.
21:53

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Podcast summary created with Snipd AI

Quick takeaways

  • Folistatin gene therapy shows promise for increasing lifespan but raises concerns with its mixed health metrics, particularly in glucose levels.
  • The complexity of evaluating gene therapies highlights the necessity for comprehensive assessment methods to accurately gauge their true effects.

Deep dives

Exploring Anti-Aging Therapies

Several anti-aging therapies are discussed, highlighting their specific effects and rankings based on research analysis. Notably, folistatin gene therapy ranks seventh in terms of lifespan extension potential, showing a significant increase in folistatin levels in mice post-treatment. This therapy stands out because it utilizes a plasmid that enhances folistatin production without altering genes, presenting a safer alternative to traditional gene editing. The exploration into gene therapy's effectiveness emphasizes the need for thorough evaluations of various markers beyond mere muscle growth, including inflammation and epigenetic aging.

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