Everyday Wellness: Midlife Hormones, Health, and Science for Women 35+

Ep. 512 The Hormone-Gut Masterclass – The Most Overlooked Fix for Women's Health with Cynthia Thurlow, NP

Oct 25, 2025
Discover the fascinating world of the gut microbiome and how it impacts women's health through puberty, pregnancy, and menopause. Learn why protein and diverse plant foods are essential in midlife, and the magic of fermented foods for gut health. Delve into the connections between sleep, stress, and hormone balance, and get practical nutrition strategies to optimize gut health. Additionally, explore the role of specific supplements and peptides that can enhance gut integrity and overall wellness. Tune in for insights on how improving gut health may alleviate menopausal symptoms!
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INSIGHT

Life Stages Reshape The Microbiome

  • Hormone shifts across puberty, pregnancy, and perimenopause reshape the gut and other body microbiomes.
  • These endocrine transitions drive immune and metabolic changes that influence lifelong health.
INSIGHT

Diversity Loss Drives Vulnerability

  • Menopause lowers microbial diversity and beneficial species like lactobacilli, reducing resilience.
  • Loss of lactobacilli promotes leaky gut, inflammation, food sensitivities, and vaginal microbiome disruption.
INSIGHT

Estrobolome Controls Estrogen Recycling

  • The estrobolome and enzymes like beta-glucuronidase manage estrogen recycling and excretion.
  • Dysfunction here can recirculate estrogens and worsen symptoms from endogenous and environmental exposures.
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