EB. 95: Hypothyroidism In Context & Thyroid Hormone Basics (Hypothyroidism Part 1)

In this episode we discuss:

• Why hypothyroidism is not the root cause of your issues
  

• Why TSH on its own is not a good marker of thyroid status

• The importance of thyroid hormones for sex hormone production, gut health, and immune function

• T3’s effects on autophagy, mitochondrial biogenesis, and uncoupling

• Whether low thyroid activity is beneficial for longevity and aging and when a high TSH may be a good sign

 

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Click here to check out the show notes: https://www.jayfeldmanwellness.com/ep-95-hypothyroidism-in-context-thyroid-hormone-basics-hypothyroidism-part-1/ 

 

Timestamps:

0:00 – intro 

1:19 – an introduction to hypothyroidism and common symptoms of hypothyroidism

9:02 – the broader biological context of hypothyroidism and hypothyroidism as a low metabolic state 

12:45 – why hypothyroidism is not the root cause

16:23 – the basics of the different thyroid hormones and their regulation

19:54 – the hypothalamic-pituitary-thyroid axis and the nuances within the negative feedback loops

24:45 – the basics of thyroid hormone production

29:37 – the basics of thyroid hormone conversion

35:17 – the larger context of thyroid hormone production and conversion

38:58 – the basics of thyroid hormone transport  

41:44 – the basics of thyroid hormone uptake

46:23 – the nutrients involved in thyroid hormone production and conversion

50:26 – the cellular effects of T3 (metabolic stimulation, uncoupling, autophagy, mitochondrial biogenesis, steroidogenesis from cholesterol)

57:29 – the effects of T3 on gut health, immune function, and aging

1:03:08 – whether low thyroid activity is beneficial for longevity and aging and when a high TSH may be a good sign

1:08:41 – the relationship between vitamin A and thyroid hormones