1) Creutzfeldt-Jakob disease and 2) Topic of the month: Apraxias. This podcast for the Neurology Journal begins and closes with Dr. Robert Gross, Editor-in-Chief, briefly discussing highlighted articles from the print issue of Neurology. In the second segment Dr. Ted Burns interviews Dr. Clive Hamlin about his paper on diagnosis of Creutzfeldt-Jakob disease. Dr. Chafic Karam is reading our e-Pearl of the week about POEMS syndrome. In the next part of the podcast Dr. Ted Burns interviews Dr. Ken Heilman about definitions for apraxia and various forms of apraxia. Dr. Burns will interview Dr. Heilman about other forms of apraxias over the next three weeks. The participants had nothing to disclose except Drs. Burns, Karam, and Heilman.Dr. Burns serves as Podcast Editor for Neurology®; performs EMG studies in his neuromuscular practice (30% effort); and has received research support from the Myasthenia Gravis Foundation of America and Knopp Neurosciences Inc..Dr. Karam serves on the editorial team for the Neurology® Resident and Fellow Section. Dr. Heilman serves as an editorial board member for ACTA Neuropsychologia, The Journal of Contemporary Neurology, Journal of the International Neuropsychological, Neurocase, Neuropsychiatry, Neuropsychology and Behavioral Neurology-Cognitive and Behavioral Neurology, Brain and Cognition, Journal of Neuropsychology and Journal of Clinical Neurology; receives royalties for the publication of Clinical Neuropsychology, fifth edition, PGY1: Lessons in Caring, Neurological Therapeutics : Principles and Practice second edition, Creativity and the Brain, Clinical Neuropsychology, fourth edition, Neurological Therapeutics : Principles and Practice, The Matter of Mind, A Neurologist's View of Brain Behavior Relationships, Apraxia, Helping People with Memory Disorders: A Guide for You and Your Family, Clinical Neuropsychology, third edition, Clinical Neuropsychology, second edition, Neuropsychology of Human Emotion, Clinical Neuropsychology and The Differential Diagnosis of Neurological Diseases; and receives funding from current (active) funded research proposals, Alzheimer's Disease Initiative State of Florida, Dept. of Elder Affairs, Memory Disorder Clinics, and the NIH.