Brain Ponderings podcast with Mark Mattson cover image

Brain Ponderings podcast with Mark Mattson

Understanding and Counteracting Brain Aging

Sep 12, 2024
59:42

In this episode I provide an overview of what happens in brain cells during aging and how those changes result in impaired brain function and predispose to Alzheimer’s and Parkinson’s diseases. I then describe three lifestyle anti-aging interventions that are known to slow brain aging and counteract disease process: physical exercise; intermittent fasting; and intellectual challenges. 

LINKS

Hallmarks of brain aging:

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6039826/pdf/nihms979409.pdf

Exercise and brain health:

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5880155/pdf/cshperspectmed-BEX-a029736.pdf

Intermittent fasting and brain health:

https://www.amazon.com/Intermittent-Fasting-Revolution-Optimizing-Performance/dp/0262046407

Environmental enrichment:

https://pubmed.ncbi.nlm.nih.gov/30723309/

Hormesis and brain health:

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6096685/pdf/10.1177_1559325818784501.pdf

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