The Dr. Gundry Podcast Alzheimer’s Isn’t Inevitable: What Science Says You Can Control Starting Now | EP 385
10 snips
Jan 6, 2026 
In this engaging discussion, Dr. Lisa Mosconi, a neurologist dedicated to women’s brain health and author of groundbreaking research, reveals that Alzheimer's is not an inevitable fate. She highlights the unique impact of menopause and estrogen on women’s brains, emphasizing personalized approaches to hormone replacement. Dr. Mosconi promotes lifestyle changes—like diet and exercise—as crucial for Alzheimer's prevention, underscoring that a healthy lifestyle can significantly reduce risks. Her insights could reshape how we view brain health.
AI Snips
Chapters
Books
Transcript
Episode notes
Women Face Higher Alzheimer’s Risk
- Women develop Alzheimer's more often than men and this difference is specific to Alzheimer's among neurodegenerative diseases.
- Hormonal differences, especially estrogen's protective effects, appear central to that sex disparity.
Alzheimer’s Begins Years Before Symptoms
- Brain changes linked to Alzheimer's begin decades before symptoms and for many women overlap with menopause.
- Menopause-related estrogen decline can correlate with early formation of Alzheimer's pathology in some women.
Prioritize Lifestyle Before Hormone Drugs
- Don't assume hormone therapy is mandatory; research on prevention via HRT is still inconclusive and needs trials.
- Prioritize lifestyle steps like diet, exercise, and stress reduction before jumping to prescriptions.
