JAMA Editors' Summary

Mobile Health Smoking Cessation for Patients With TB, Nirsevimab vs Maternal RSVpreF Vaccine for RSV Prevention in Newborns, Self-Care and Spinal Manipulation for Low Back Pain, and more

Jan 2, 2026
Discover how mobile health texts can significantly aid TB patients in quitting smoking. Learn about innovative strategies in preventing infant RSV through nirsevimab versus maternal vaccination. Explore findings that reveal modest benefits of self-management and spinal manipulation for low back pain. Also, hear about the impressive impact of lay worker symptom check-ins on reducing emergency visits for cancer patients. Finally, dive into the rapid rise of private equity in IVF clinics and the implications for healthcare.
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ADVICE

Text Support Boosts TB Smoking Cessation

  • Use low-cost text messaging to support tobacco cessation during TB treatment.
  • The mHealth program increased six-month continuous abstinence from 15.3% to 41.7% and reduced deaths.
INSIGHT

Infant Antibody Outperformed Maternal Vaccine

  • Direct infant immunization with nirsevimab prevented more RSV hospitalizations than maternal RSVpreF vaccination.
  • The nirsevimab group had fewer ICU admissions and less need for ventilator or oxygen support.
INSIGHT

Self-Management Reduces Back Disability

  • Clinician-supported self-management modestly reduced disability from acute/subacute low back pain.
  • Spinal manipulation alone showed no benefit over guideline-based medical care.
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