Explore practical strategies for managing common antidepressant side effects in the pediatric population, such as activation, insomnia, and withdrawal symptoms. Learn about the complexities of discontinuation effects and tailoring treatment approaches for better outcomes in youth.
Proactively educate patients about antidepressant side effects to manage them effectively.
Manage persistent hyperhidrosis from antidepressants with low-dose glycopyrrolate or topical agents.
Deep dives
Early and Late Emerging Side Effects of Antidepressants in Youth
Antidepressants, such as SSRIs and SNRIs, are commonly used to treat neuropsychiatric disorders in children and adolescents. These medications can result in both early, like activation and GI symptoms, which are often transient, and late emerging side effects, including weight gain and sexual dysfunction. It is crucial to proactively educate patients and parents about these potential side effects and manage them by adjusting doses or using a gradual escalation approach.
Managing Hyperhidrosis as a Persistent Side Effect
Hyperhidrosis, characterized by increased sweating, is a persistent side effect associated with some antidepressants due to their affinity for dopamine receptors. This condition can be managed with low-dose glycopyrrolate, available in oral formulations. Hyperhidrosis, more common with second-generation antidepressants, can be effectively addressed with appropriate medications, like oral glycopyrrolate or topical agents. Behavioral sleep hygiene practices are recommended as a first line of treatment for persistent SSRI or SNRI-induced insomnia in children and adolescents.
Considerations for Headaches in Youth with Anxiety and Depression
Headaches, commonly reported in youth receiving antidepressant treatment, are also prevalent in depressive and anxiety disorders. Tricyclic antidepressants and 5HT1B and 1D agonists can be considered for treating headaches and potentially preventing their occurrence. Proper assessment of baseline functioning and symptoms is essential before initiating medication to differentiate between side effects and primary symptoms of anxiety or depression.
In this podcast episode, Dr. David Rosenberg explores practical strategies to asess and manage common antidepressant side effects in the pediatric population. Get useful takeaways regarding activation, insomnia, withdrawal symptoms, and more.
Faculty: David Rosenberg, M.D. Host: Richard Seeber, M.D.