
Psychopharmacology and Psychiatry Updates
Practical psychopharmacology updates for mental health clinicians. Useful for psychiatry / mental health professionals. Expert interviews and soundbites from CME presentations. Practical and free of commercial bias. Not sponsored by any pharmaceutical company.
Latest episodes

Jun 15, 2025 • 15min
Demystifying Benzodiazepine Deprescribing: Smart Approaches to Tapering
Alexis Ritvo, a board-certified addiction psychiatrist and fellowship director at the University of Colorado, dives into the complexities of tapering benzodiazepines. She shares evidence-based strategies such as 'cut-and-hold' and 'microtaper' techniques tailored for patient comfort. The discussion emphasizes personalized approaches that enhance safety during withdrawal, alongside the challenges of dosage precision and patient adherence. By highlighting case studies, Ritvo showcases the importance of supportive therapies in navigating benzodiazepine deprescribing.

Jun 10, 2025 • 10min
Lithium: Implications for Bone Health
In this episode, we explore lithium's surprising positive effect on bone mineral density in patients with bipolar disorder. Could the medication many psychiatrists use as a mood stabilizer also be protecting patients from osteoporosis? Faculty: Paul Zarkowski, M.D. Host: Richard Seeber, M.D. Learn more about our membership here Earn 0.5 CME: Quick Take Vol. 68 Can Lithium Protect Against Osteoporosis?

Jun 5, 2025 • 16min
Tapering with Care: Benzodiazepine Discontinuation
In this episode, we explore evidence-based strategies for successful benzodiazepine tapering with addiction psychiatrist Dr. Alexis Ritvo. How can clinicians minimize withdrawal effects while supporting patients through this challenging process? Faculty: Alexis Ritvo, M.D. Host: Richard Seeber, M.D. Learn more about our membership here Earn 1.25 CMEs: Strategies for Successful Benzodiazepine Deprescribing Understanding the Principles of Benzodiazepine Tapering

May 31, 2025 • 11min
Dementia Risk and Vitamin D
Scott Beach, a faculty member at the Psychopharmacology Institute, dives into the intriguing findings from the UK Biobank study. He reveals how vitamin D deficiency might elevate dementia risk by up to 25%. The discussion emphasizes the importance of monitoring vitamin D levels, especially in older adults, and suggests that this affordable supplement could be key in bolstering brain health. Beach also highlights the notable differences linked to skin color and gene type, making a compelling case for dietary interventions to promote cognitive well-being.

May 26, 2025 • 14min
Beyond Benzos: Strategies for Successful Deprescribing
In this insightful discussion, Alexis Ritvo, a board-certified addiction psychiatrist and esteemed program director at the University of Colorado, shares expert insights on benzodiazepine deprescribing. The conversation tackles the balance between benefits and withdrawal challenges, emphasizing patient-centered care. Ritvo highlights the importance of education, informed consent, and open dialogue, showcasing findings from the Empowered Trial. Strategies to help patients safely reduce their dependence on these medications are explored, ultimately promoting better mental health outcomes.

May 21, 2025 • 12min
Motherhood and Medication: LAIs for Women with Schizophrenia
Oliver Freudenreich, a seasoned psychiatrist from Boston, delves into the complexities of treating women with schizophrenia using long-acting injectable antipsychotics. He highlights the impact of hormonal fluctuations, particularly during pregnancy and postpartum, on medication efficacy. The discussion also covers the unique challenges women face regarding treatment adherence and the need for personalized strategies. Freudenreich emphasizes how these tailored approaches can significantly improve stability and support for women during critical life transitions.

May 16, 2025 • 10min
Benzodiazepines in High-Risk Populations
Discover the complexities surrounding benzodiazepine use in high-risk populations such as pregnant women, nursing mothers, and adolescents. The discussion highlights the potential risks and necessary precautions, emphasizing the need for cautious prescription practices. Learn about the delicate balance between benefits and risks, and explore alternatives for safer management. Key insights focus on fostering coping skills to address the challenges at these critical life stages.

May 11, 2025 • 12min
Benzodiazepines: Understanding Physical Dependence vs. Addiction
Alexis Ritvo, a board-certified addiction psychiatrist and Assistant Professor at the University of Colorado, shares insights on benzodiazepine use disorder. She clarifies the crucial distinction between physical dependence and addiction. Surprisingly, only 1.5% of users develop a use disorder despite common concerns. The discussion delves into responsible prescribing practices and the necessity of monitoring for potential misuse. Listeners gain valuable knowledge on recognizing warning signs and promoting safe medication use.

May 6, 2025 • 13min
Beyond Metformin: Probiotics and Antipsychotic Weight Gain
Dr. Oliver Freudenreich, a Boston-based psychiatrist, dives into the fascinating world of probiotics and their potential to combat weight gain linked to antipsychotics like olanzapine. He discusses the probiotic Akkermansia muciniphila, suggesting it could be key to maintaining metabolic health. The conversation explores how gut health impacts weight management for patients on antipsychotics. Dr. Freudenreich also highlights the challenges of incorporating probiotics into treatment, paving the way for a holistic approach to psychiatric care.

8 snips
May 1, 2025 • 10min
What Every Clinician Should Know About the Risks of Benzodiazepines
Dive into the alarming risks of benzodiazepines, especially when mixed with opioids, which can increase overdose chances fivefold in just 90 days. Discover how these drugs contribute to cognitive decline and accident hazards, particularly in older adults. Statistics reveal a rising trend in overdose deaths among women aged 30 to 64, underscoring the urgency for safer prescribing practices. Explore alternative treatments for anxiety that promise a healthier approach while emphasizing the need for informed decisions in clinical settings.