This Podcast Will Kill You cover image

This Podcast Will Kill You

Ep 30 Encephalitis Lethargica: Sleep Perchance to Dream (& Dream & Dream)

Jun 25, 2019
Discover the mysterious epidemic of encephalitis lethargica, a 'sleepy sickness' that afflicted millions in the early 1900s. Learn about the impact and clinical varieties of this illness, including post-encephalitic Parkinsonism and its treatments with L-DOPA. Delve into the uncertainty about its cause and the potential resurgence of this forgotten medical mystery.
01:27:51

Podcast summary created with Snipd AI

Quick takeaways

  • Encephalitis lethargica had three main forms: somnolent, hyperkinetic, and amisotic kinetic, each with distinct symptoms and outcomes.
  • Brain changes in the illness included vessel congestion, hemorrhages, and neurofibrillary tangles, affecting movement control areas and presenting unique challenges for treatment.

Deep dives

Types of Encephalitis Lethargica

Encephalitis lethargica presents in three main forms: the somnolent form, characterized by intense sleepiness leading to a deep slumber sometimes resulting in death; the hyperkinetic form presents as restlessness, muscle twitching, and insomnia progressing to sleepiness; and the amisotic kinetic form showcases muscle weakness, rigidity similar to Parkinson's, without the characteristic tremors.

Get the Snipd
podcast app

Unlock the knowledge in podcasts with the podcast player of the future.
App store bannerPlay store banner

AI-powered
podcast player

Listen to all your favourite podcasts with AI-powered features

Discover
highlights

Listen to the best highlights from the podcasts you love and dive into the full episode

Save any
moment

Hear something you like? Tap your headphones to save it with AI-generated key takeaways

Share
& Export

Send highlights to Twitter, WhatsApp or export them to Notion, Readwise & more

AI-powered
podcast player

Listen to all your favourite podcasts with AI-powered features

Discover
highlights

Listen to the best highlights from the podcasts you love and dive into the full episode