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The International Space Station (ISS) has played a pivotal role in scientific advancements since its launch in 1998, operating as a symbol of international collaboration. After nearly three decades in orbit, the ISS is nearing its end, with its structural integrity declining and only six years remaining before it is decommissioned and deorbited into the Pacific Ocean. The ISS has made significant contributions, including breakthroughs in medicine, climate monitoring, and the study of human biology in microgravity, showcasing the potential of science when nations work together. This legacy highlights the importance of maintaining international cooperation in space exploration going forward.