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Febrile
76: Pièce de (Gram-negative) Resistance, Part 1: AmpC, ESBL
Jun 26, 2023
This podcast discusses the management of antimicrobial resistant Gram-negative infections, focusing on AmpC and ESBL. It explores treatment options for ESBL producers, the potential use of amineaglicocytes for urinary tract infections, antibiotic choices for perforated diverticulitis and serious infections, and antibiotic resistance in Gram-negative organisms.
53:06
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Quick takeaways
- Preferred antibiotics for ESBL E. coli infections are trimethoprim-sulfamethoxazole, ciprofloxacin, or levofloxacin.
- Cephalpine is suggested for moderate to high-risk infections caused by AMPC-producing organisms like Club Celah Aerogenes.
Deep dives
ESBL E. coli Palaeinofritis Treatment
The preferred antibiotics for complicated UTI or palaeinofritis caused by ESBL E. coli are trimethoprim-sulfamethoxazole, ciprofloxacin, or levofloxacin. Carbapenems are preferred when resistance or toxicity prevents the use of the first-line agents.
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Discover
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