Treatment options for ESBL producers

This chapter explores the treatment options for extended spectrum beta-lactamase (ESBL) producers, specifically discussing cephalosporin, piperacillin-tazobactam, and carbapenem. It examines observational data and clinical trials comparing these drugs, highlighting concerns about the efficacy of piperacillin-tazobactam based on higher mortality rates in a trial. The speaker concludes that they are not enthusiastic about using piperacillin-tazobactam for bacteremia and pyelonephritis.