This Podcast Will Kill You Ep 146 Celiac Disease: Rootin tootin gluten
Jul 23, 2024
Delving into the history and biology of gluten intolerance and celiac disease. Exploring the impact on mental health, navigating life with dietary restrictions, and understanding the autoimmune nature of the condition. Discussing the rise of gluten-free trends, global prevalence, challenges in diagnosis, and promising therapeutic research.
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Becca's Celiac Journey
- Becca was diagnosed with celiac disease at age 11 after experiencing stomach aches and a traumatic blood test.
- A biopsy confirmed the diagnosis, leading to a significant mental and physical health journey.
Celiac Disease Explained
- Celiac disease is an autoimmune disorder where the body attacks gluten, causing small intestine inflammation.
- Gluten is a protein complex found in wheat, rye, and barley, with gliadin being the main culprit in celiac disease.
Celiac Genetics
- Over 99% of celiac patients have specific HLA markers (DQ2 or DQ8), showing a strong genetic link.
- These HLA proteins present gluten to T cells, triggering an immune response in the gut.