EP 198 When Hormones Hurt: PMDD (Premenstrual Dysphoric Disorder)

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In this episode of the Conquering Your Fibromyalgia podcast, Dr. Michael Lenz delves into the complex relationship between hormones and chronic pain conditions such as fibromyalgia, migraines, dysmenorrhea, and others. The focus is on Premenstrual Dysphoric Disorder (PMDD), exploring the impact of estrogen and progesterone fluctuations on pain perception and symptom management. Key studies are discussed to highlight the relationship between menstrual cycles and fibromyalgia symptoms. The episode also covers the genetic, neurobiological, and environmental factors contributing to PMDD, as well as treatment options ranging from SSRIs and hormonal treatments to lifestyle changes and cognitive behavioral therapy. The intricate link between ADHD in women and mood disorders like PMDD and depression is also examined.

00:00 Introduction to Hormones and Chronic Pain
00:56 Understanding Hormonal Fluctuations
02:26 Clinical Studies on Hormones and Pain
03:48 The Role of Estrogen and Progesterone
04:42 Historical Perspective on Premenstrual Disorders
06:28 Diagnosing PMDD: Symptoms and Criteria
07:39 Causes and Brain Sensitivity in PMDD
09:35 Genetic and Neurobiological Factors
10:45 Serotonin and Allopregnanolone in PMDD
12:06 Stress, Inflammation, and PMDD
13:33 Treatment Options: SSRIs and Hormonal Therapies
16:26 Advanced Treatments and Surgical Options
21:06 ADHD and Hormone-Related Mood Disorders
27:43 Managing PMDD: Lifestyle and Non-Pharmacological Approaches
31:12 Conclusion and Final Thoughts

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A Fibromyalgia Starter Pack, a great companion to the book Conquering Your Fibromyalgia, is now available. Dr. Michael Lenz practices general pediatrics and internal medicine primary care, seeing patients from infants through adults. In addition, he also will see patients with fibromyalgia and related problems and patients interested in lifestyle medicine and clinical lipidology. To learn more, go to ConquringYourFibromyalgia.com. Remember that while Dr. Lenz is a medical doctor, he is not your doctor. All of your signs and symptoms should be discussed with your physician. He aims to weave the best of conventional medicine with lifestyle medicine to help people with chronic health conditions live their best lives possible. Dr. Lenz hopes that the podcast, book, blog, and website serve as a trusted resource and starting point on your journey of learning to live better with fibromyalgia and related illnesses.

Junior Producer- Brooklyn Lenz