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PedsCrit
Corticosteroids in Septic Shock with Dr. Jerry Zimmerman Part 2
Aug 21, 2023
Dr. Jerry Zimmerman, Professor of Pediatrics, discusses the physiologic rationale and clinical evidence for using corticosteroids in septic shock. They explore the potential benefits and adverse effects of corticosteroids in conditions like COVID-19 and ARDS. They also discuss the use of oxandrolone for muscle protein accretion and the future of clinical research. Additionally, they cover the use of corticosteroids in adrenal insufficiency, ACTH stimulation tests, and optimal cortisol cutoffs.
26:39
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Quick takeaways
- The decision to prescribe corticosteroids in critically ill patients depends on various factors like patient history and severity of condition, and appropriate dosage can be determined through serum calcium check and random cortisol test.
- Different clinical scenarios require different indications for administering corticosteroids, such as primary adrenal insufficiency, chronic steroid use, and specific conditions like COVID-19 and ARDS, highlighting the need for further research and platform trials in pediatric sepsis.
Deep dives
The use of corticosteroids in critically ill patients
The podcast episode discusses the use of corticosteroids in critically ill patients, specifically focusing on the dose and indications for administering hydrocortisone. The speaker explains that the decision to prescribe corticosteroids depends on various factors such as the patient's history, the presence of comorbidities, and the severity of the patient's condition. They emphasize the importance of checking serum calcium, considering the patient's history, and conducting a random cortisol test to determine the appropriate dosage. The speaker also highlights the need to balance the benefits of corticosteroids with their potential adverse effects, highlighting the complexities of monitoring side effects and optimizing patient outcomes.
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Discover
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Listen to the best highlights from the podcasts you love and dive into the full episode