Making Sense with Sam Harris

#306 — Psychedelics & Mortality

112 snips
Dec 13, 2022
Roland Griffiths, a leading researcher in psychedelics from Johns Hopkins University, delves into the transformative potential of psychedelics while grappling with his own stage-4 cancer diagnosis. The conversation highlights the fascinating intersections of psychedelics and meditation, their therapeutic promises, and the need for responsible use. Griffiths shares personal reflections on mortality, fear, and gratitude, urging a deeper understanding of life through these experiences. They also discuss the exciting advances in psychedelic research and the importance of nurturing public discourse on these substances.
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INSIGHT

Psychedelic Research Progress

  • The psychedelic research landscape is rapidly changing, with more academic centers and NIH funding.
  • Clinical trials for MDMA and psilocybin are progressing toward FDA approval for specific conditions.
ADVICE

Medicalization of Psychedelics

  • Prioritize medicalization of psychedelics within regulated institutional structures.
  • This approach mitigates risks, ensures proper set and setting, and normalizes psychedelic use.
INSIGHT

Psychedelics and Schizophrenia

  • While a causal link between psychedelics and schizophrenia hasn't been definitively proven, anecdotal cases suggest caution is warranted.
  • Individuals with family histories of psychotic disorders should be screened carefully.
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