Nicotamide and Paradoxine for Muscle Aging

Nicotamide and paradoxine are identified as natural nutrients that can reverse muscle aging, particularly important for individuals over 40. A study from the Journal of Clinical Investigations revealed that these compounds support muscle stem cells by mediating B-catenin signaling and stimulating AKT pathways, which are crucial for muscle proliferation and differentiation. As muscles naturally shrink with age, incorporating these nutrients can help maintain muscle mass and overall strength. Therefore, individuals taking NAD supplements or B complex vitamins are benefiting from these muscle-supporting effects.