TED Talks Daily A new type of medicine, custom-made with tiny proteins | Christopher Bahl
Jan 28, 2020
Discover the future of medicine with custom-designed peptides that are smaller and more robust than traditional proteins. These innovations might transform treatments for everything from the flu to cancer. Learn how molecular engineering is paving the way for personalized healthcare and potentially lifesaving therapies. With a focus on the stability and effectiveness of constrained peptides, the talk reveals exciting possibilities in drug development and disease treatment.
AI Snips
Chapters
Transcript
Episode notes
Constrained Peptides: A New Type of Medicine
- Constrained peptides are small, stable, and potent proteins used in new medicines.
- They offer advantages of both small molecule drugs and biologics.
Challenges of Re-engineering
- Re-engineering natural constrained peptides for drug development is challenging.
- Changing their shape can disrupt the bonds, causing the molecule to fall apart.
Building Peptides From Scratch
- A collaborative effort developed open-source software for designing peptides from scratch.
- They tested the software by creating peptides with various shapes, some new to nature.