Historical Impact of Psychedelics on Headache Medicine

Psychedelics have played a crucial role in headache medicine, dating back to the late 19th century when indigenous knowledge of plant medicines influenced the use of peyote for treating headaches. In the mid-20th century, LSD was studied for its potential in treating migraines, leading to the creation of Sansert, a medication used for both migraine and cluster headache prevention. This historical context emphasizes the need to revisit psychedelic substances as a legitimate research option for challenging health issues, highlighting their potential beyond traditional pharmaceutical approaches.