This Podcast for the Neurology Journal begins with Dr. John H. Noseworthy, Editor-in-Chief, briefly discussing highlighted articles from the print issue of Neurology. In the second segment Drs. E. Clarke Haley and Brett Kissela interview Dr. Juan F. Arenillas about his paper on metabolic syndrome and resistance to IV thrombolysis. The podcast concludes with Dr. Fadi Nahab interviewing Dr. Tanya Turan for the Lesson of the week. The participants had nothing to disclose.