Age Less / Live More 606: The Future of Longevity Medicine with Dr. Charles Brenner
“I don’t know the meaning of life, but I know the purpose of life: to survive and procreate.” This quote was from a biologist on the podcast eight years ago, and it stuck with me because if he’s right, I’ve achieved my biological imperative and I’m now on borrowed time. While that may sound soulless and even nihilistic, it’s also a helpful frame (for me) as I attempt to make choices to optimize my life in the second half - my bonus time. On this week’s podcast, you’ll meet a researcher who debunks many pop longevity myths and also shares some compelling research around the supplement nicotinamide riboside. Will it make you live forever? No, but it might help you live better for the time you are here.
Listen and learn:
- Why “biological age” tests are inaccurate
- How we’re unlikely to experience “escape velocity”
- Metformin, rapamycin, and resveratrol debunked
- Why so-called longevity clinics giving TRT and HGH are almost certainly reducing - not extending - lifespan
Links
ABOUT OUR GUEST
Dr. Charles Brenner, the Alfred E. Mann Family Foundation Chair in Diabetes and Cancer Metabolism at City of Hope National Medical Center, discovered nicotinamide riboside (NR) as a crucial precursor to NAD+ in 2004 and a second NR-to-NAD+ conversion pathway in 2007, enhancing yeast cell lifespan. Currently, Dr. Brenner leads groundbreaking clinical trials on NR, focusing on its maternal and neonatal effects and translating animal model findings into safe, evidence-based clinical practices for human metabolic stress conditions.
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