JAMA Clinical Reviews

Diverticulitis: Diagnosis and Management

Jul 24, 2025
Dr. Anthony Charles is a Professor of Surgery and Chief of Trauma and Acute Care Surgery at the University of Vermont. He discusses the alarming rise of diverticulitis cases, especially in younger populations. Key insights include the impact of dietary choices on the condition and the essential diagnostic tools like CT scans. The conversation highlights the tailored approach to treatment, potential complications, and the timing for follow-up colonoscopies. Charles emphasizes the need for urgent responses to complications to ensure better patient outcomes.
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INSIGHT

What is Diverticulitis?

  • Diverticula are outpouchings of the bowel wall's mucosa and submucosa.
  • Diverticulitis is inflammation of these diverticula.
INSIGHT

Who is at Risk?

  • Older adults over 65 are at higher risk for diverticulosis and diverticulitis.
  • Certain inherited connective tissue disorders also increase risk.
INSIGHT

Uncertain Role of Diet

  • The role of diet in diverticulosis is uncertain despite historical belief in Western diet influence.
  • Colonoscopy-based studies showed no difference between high and low fiber diets regarding diverticulosis presence.
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