

Does Ozempic Work?
14 snips Apr 17, 2025
The complex effectiveness of GLP-1 agonists like Ozempic is scrutinized in detail. Historical concerns about weight loss drugs are highlighted, raising questions about safety. Listeners learn about the modest results these medications yield and what long-term implications they might hold for those seeking weight loss. A thoughtful examination captures the nuances behind this popular treatment.
AI Snips
Chapters
Books
Transcript
Episode notes
History of Dangerous Weight Drugs
- Most anti-obesity drugs approved for safety have later been withdrawn due to serious side effects. - History includes pills causing lung damage, heart problems, cancer, and psychiatric issues.
GLP-1 Drugs vs Older Medications
- Older weight loss drugs caused about 5% weight loss, while new GLP-1 agonists like Ozempic cause about 6%. - New drugs like semaglutide cause roughly double the weight loss of older GLP-1 drugs, and one newer drug approaches effects of bariatric surgery.
How GLP-1 Drugs Work
- GLP-1 is a gut hormone signaling nutrient abundance and reducing appetite. - GLP-1 drugs mimic this hormone, tricking the body into feeling full and reducing hunger.