Self-Funded With Spencer Fixing Healthcare's 528 Billion Dollar Mistake | with Chris Grilli
Sep 3, 2025
Chris Grilli, a pharmacist and genomics expert at RxMapper, dives deep into the staggering $528 billion wasted on medication errors in healthcare. He reveals how personalized, DNA-guided medicine can dramatically reduce these costs and improve patient outcomes with nearly 90% accuracy. Chris shares a personal story that inspired him to develop RxMapper after a family tragedy, and he discusses the powerful role genetics plays in medication efficacy. Tune in to learn how this innovative approach is set to revolutionize healthcare!
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The $528B Medication Waste Problem
- The US spends about $528 billion annually treating medication mistakes rather than preventing them.
- Genomics can dramatically reduce that waste by guiding initial drug selection to improve efficacy and safety.
Scale Of Genomic Data Drives Accuracy
- RxMapper sequences ~36 million genomic data points per patient versus narrow pharmacogenomic panels.
- That scale lifts meaningful recommendations from ~3–4% to roughly 90% of cases they screen.
A Personal Tragedy Sparked RxMapper
- Chris's grandmother died from a preventable bleeding complication tied to family genetics.
- That personal tragedy motivated him to build RxMapper to prevent similar adverse drug events.