

EP 116: Genetics and Medicine: Clonal hematopoiesis, genomics in healthcare, and a new discovery in APOL1 kidney disease with Dr. Alex Bick
Jan 4, 2024
Dr. Alex Bick, an Assistant Professor of Medicine at Vanderbilt, dives deep into clonal hematopoiesis, linking it to aging, cancer, and heart disease. He discusses groundbreaking findings from the Framingham Heart Study, revealing how clonal expansion can predict health risks. Bick also examines the significance of integrating genomic data into healthcare and highlights discoveries regarding the APOL1 gene's role in kidney disease, showcasing the impact of large-scale studies like the Million Veteran Project.
Chapters
Transcript
Episode notes
1 2 3 4 5 6 7
Intro
00:00 • 2min
Unraveling Clonal Hematopoiesis
01:45 • 16min
Integrating Genomics in Health Risk Assessment
18:06 • 10min
Exploring APOL1 and Kidney Disease
28:22 • 11min
Unlocking Genetic Secrets: The Role of APOL1 in Disease Resistance
39:21 • 2min
Investigating Genetic Haplotype Impacts on Kidney Disease Risk
41:13 • 3min
Navigating Diversity in Genetic Research
44:00 • 8min