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EP 116: Genetics and Medicine: Clonal hematopoiesis, genomics in healthcare, and a new discovery in APOL1 kidney disease with Dr. Alex Bick

The Genetics Podcast

CHAPTER

Unraveling Clonal Hematopoiesis

This chapter examines the intriguing world of clonal hematopoiesis, particularly its association with aging, precancerous mutations, and increased heart disease risk. Through insights from the Framingham Heart Study, it highlights the dual implications of clonal hematopoiesis on both blood cancer and cardiovascular health, stressing the complexity of genetic mutations. The conversation also addresses ongoing research into measuring clonal expansion and its impact on health outcomes, particularly in older adults.

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