Episode 164: Deep Dive Into Cholesterol with Dr. Kirsten Gurtowsky
Feb 14, 2023
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Discover the complexities of cholesterol with Dr. Gurtowsky as they discuss lab markers, genetic root causes in dyslipidemia, treatment options like Bempedoic acid and niacin, and the impact of genetics on heart health. Learn about vitamin K2's role, strategies to lower LDL, and the importance of personalized healthcare practices.
Cholesterol treatment is based on guidelines and risk factors, including genetic influences and the Coronary Calcium Score for assessing cardiovascular risks.
Lowering LDL levels through medication, lifestyle changes, and genetic considerations can significantly reduce cardiovascular risks and guide treatment options.
Advanced testing, genetic factors, dietary choices, and supplement use are crucial in managing cholesterol levels and heart health for high-risk patients.
Deep dives
Understanding Cholesterol and its Impact on Health
Cholesterol is a crucial topic in heart disease discussions. LDL and HDL are key lipoproteins that carry cholesterol in the body. While cholesterol is essential for cellular functions, excessive LDL can lead to arterial plaque build-up, increasing cardiovascular risks. Statins are the primary drug therapy, with options like Bempedoic acid for LDL control.
Determining Cholesterol Treatment Needs
Healthcare providers assess the need for cholesterol treatment based on guidelines and risk factors. Patients with high LDL or conditions like diabetes require statin therapy. The Coronary Calcium Score helps evaluate the risk of plaque build-up in arteries. Genetic factors like LPA little a play a vital role in assessing cardiovascular risks.
Implications of Low LDL and Dietary Factors
Lower LDL levels are associated with reduced cardiovascular risks, and there is no specific 'too low' point determined. While food contributes minimally to cholesterol levels, unhealthy fats and sugars can impact inflammation and heart health. Supplements may help moderately lower cholesterol, but overall genetic factors play a significant role.
Emerging Concepts in Cardiovascular Health
Vitamin K2 supplements are being studied for their potential to prevent plaque formation and improve heart health. LPA little a is a genetic risk factor independent of cholesterol that significantly impacts cardiovascular risk. Monitoring particle size and number of lipoproteins may provide additional insights for high-risk patients.
Future Considerations for Cardiovascular Health
Recent research highlights the importance of genetic factors like LPA little a, which significantly increase the risk of heart disease. Advanced tests like particle size evaluation and monitoring homocysteine levels can offer valuable insights into cardiovascular health. Dietary choices, supplement use, and genetic predispositions play key roles in managing cholesterol and heart health.