The Clinical Problem Solvers
Episode 311: Spaced Learning Series – Hypercalcemia
Nov 21, 2023
Experts in hypercalcemia, seizure management, and vision loss discuss a case of severe hypercalcemia, seizures, and vision impairment. They delve into the significance of parathyroid hormone levels in diagnosing parathyroid disorders and explore the differential diagnoses for the patient's symptoms. They also discuss the potential long-term effects of hypercalcemia on vision and the importance of expanding understanding in this area.
32:38
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Quick takeaways
- Hypercalcemia can rarely cause vision loss and seizures.
- Differential diagnosis is important in evaluating hypercalcemia, distinguishing primary hyperparathyroidism from malignancy/endocrine disorders.
Deep dives
Severe Hypercalcemia with Neurological Symptoms
The podcast discusses a case of a 15-year-old girl presenting with diffuse abdominal pain, nausea, vomiting, weight loss, sudden vision loss, and a seizure. The doctors focus on severe hypercalcemia as a possible cause, which can explain some of the symptoms such as gastrointestinal distress and hypertension. However, they note that hypercalcemia rarely causes vision loss and seizures. They also mention the importance of considering differential diagnoses for hypercalcemia, particularly differentiating between primary hyperparathyroidism and other conditions related to malignancy or endocrine disorders.
