No Priors: Artificial Intelligence | Technology | Startups Why Cryopreservation is No Longer Science Fiction with Until Co-founder and CEO Laura Deming
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Jan 29, 2026 
Laura Deming, biotech entrepreneur and longevity investor turned CEO of Until, explores reversible cryopreservation. She discusses pausing biological time to save organs, why ice destroys tissue, engineering tricks for cooling and rewarming, and scaling from organs to whole-body hibernation. The conversation highlights clinical uses, technical trade-offs, and how removing time could transform transplantation logistics.
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Ice Is The Core Problem In Cryopreservation
- Ice formation is the core physical barrier to reversible cryopreservation and causes tissue damage by expansion.
- Avoiding nucleation and traversing below the critical temperature window is the main technical strategy.
A Missed Therapy Sparked The Mission
- Laura shares Hunter's father-in-law missed a critical cancer therapy by months and would have benefited from pause technology.
- That personal story motivates Until's focus on buying time for patients to reach new treatments.
Pause Biological Time To Buy Critical Months
- Until's long-term aim is whole-body reversible cryopreservation for medical hibernation.
- Near-term focus is reversibly preserving single human organs to improve transplant logistics.