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Psychopharmacology and Psychiatry Updates

Breaking the Cycle: Memantine in Body-Focused Repetitive Behaviors

Nov 7, 2024
Dr. Robert Hudak, a psychiatrist from the OCD program at the University of Pittsburgh, unveils promising insights into treating trichotillomania and skin-picking disorder with memantine, typically an Alzheimer's medication. He shares compelling study results indicating that memantine could notably improve symptoms, particularly in severe cases. The discussion highlights the need for greater awareness and screening among clinicians, as well as the importance of a comprehensive treatment approach that includes psychotherapy.
10:13

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Quick takeaways

  • Memantine shows a significant response rate of 60% in treating body-focused repetitive behaviors compared to 8.3% for placebo, indicating its potential as a breakthrough treatment.
  • Despite promising results, further research is needed to include more severe cases and develop standardized assessment tools for body-focused repetitive behaviors.

Deep dives

Understanding Body-Focused Repetitive Behaviors (BFRBs)

Body-focused repetitive behaviors (BFRBs), such as trichotillomania (hair pulling) and skin picking disorders, affect approximately 2% of the population. These conditions are often misclassified as mere bad habits, leading to underdiagnosis and improper treatment. Despite their prevalence, many individuals with BFRBs do not report their conditions due to feelings of shame, believing these compulsions are secondary to anxiety or stress. The serious nature of these disorders can result in significant psychological distress and even life-threatening complications, further underscoring the need for increased awareness and appropriate clinical screening.

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