Non-transplant Options in Pediatric Acute Liver Failure by A. Deep | OPENPediatrics

In this World Shared Practice Forum podcast, Dr. Akash Deep, Director of the Pediatric Intensive Care Unit, Staff Governor, and Professor in Pediatric Critical Care at King’s College Hospital, discusses his recent publication on non-transplant options in pediatric acute liver failure. He describes important considerations for the management of acute liver failure and commonly associated toxicities, and offers insights into the paradigm shift currently evolving in the field and what we can expect in the trends of future treatment pathways. Upon listening to this presentation, learners should be able to: - Apply strategies for management of acutely ill children with acute liver failure - Describe various forms of toxicity commonly associated with acute liver failure Publication date: June 28, 2022. Articles Referenced: • Deep A, Nagakawa S, Tissieres P. Non-transplant options in paediatric acute liver failure-what is new?. Intensive Care Med. 2022;48(1):114-117. (00:49) • Habib M, Roberts LN, Patel RK, Wendon J, Bernal W, Arya R. Evidence of rebalanced coagulation in acute liver injury and acute liver failure as measured by thrombin generation. Liver Int. 2014;34(5):672-678. (7:03) • Slack AJ, Auzinger G, Willars C, et al. Ammonia clearance with haemofiltration in adults with liver disease. Liver Int. 2014;34(1):42-48. (13:27) • Hunt A, Tasker RC, Deep A. Neurocritical care monitoring of encephalopathic children with acute liver failure: A systematic review. Pediatr Transplant. 2019;23(7):e13556. (17:39) • Kochanek PM, Adelson PD, Rosario BL, et al. Comparison of Intracranial Pressure Measurements Before and After Hypertonic Saline or Mannitol Treatment in Children With Severe Traumatic Brain Injury. JAMA Netw Open. 2022;5(3):e220891. (19:51) Citation: Deep A, Daniel D, Burns JP. Non-transplant Options in Pediatric Acute Liver Failure. 6/2022. Online Podcast. OPENPediatrics. https://youtu.be/iSvZ26drzy0. Please visit: www.openpediatrics.org OPENPediatrics™ is an interactive digital learning platform for healthcare clinicians sponsored by Boston Children's Hospital and in collaboration with the World Federation of Pediatric Intensive and Critical Care Societies. It is designed to promote the exchange of knowledge between healthcare providers around the world caring for critically ill children in all resource settings. The content includes internationally recognized experts teaching the full range of topics on the care of critically ill children. All content is peer-reviewed and open access-and thus at no expense to the user. For further information on how to enroll, please email: openpediatrics@childrens.harvard.edu Please note: OPENPediatrics does not support nor control any related videos in the sidebar, these are placed by Youtube. We apologize for any inconvenience this may cause.