

Beware: The First Sign of Heart Disease - And What to Do Next ft. Zachary Lott NP - Ford Brewer MD MPH (PrevMed Health)
Aug 27, 2025
Zachary Lott, a nurse practitioner specializing in cardiometabolic disease prevention, dives into the early signs of heart disease and the importance of proactive health measures. He discusses how erectile dysfunction can signal cardiovascular risks, particularly in younger men. Lott emphasizes the innovative CardioRisk IMT test for assessing vascular health, revealing distressing cases of young patients with aged arteries. The conversation highlights the need for timely screenings and improved diagnostics to empower individuals to take charge of their heart health.
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ED As Early Cardiovascular Signal
- Erectile dysfunction often appears long before heart disease and signals microvascular problems.
- Zachary Lott calls ED the "canary in the coal mine" for men's cardiovascular risk.
26-Year-Old With 56-Year Arteries
- A 26-year-old man had an arterial age of 56 on CIMT despite his young chronological age.
- Zachary Lott found bilateral soft plaque that revealed severe early disease.
Ultrasound Strongly Predicts Risk
- Point-of-care carotid/femoral ultrasound (CIMT) predicts 10-year risk far better than many calculators.
- Zachary Lott cites about 98.6% accuracy stratifying risk using the Cafe-Cave approach.