Age-related macular degeneration, glaucoma, diabetic retinopathy, and genetic disorders such as retinitis pigmentosa are major causes of blindness. In this episode Professor Russ van Gelder at the University of Washington talks about exciting advances in vision restoration using retinal cell replacement, gene therapy, visual prosthetic devices, and small molecule ‘photoswitches’. Several of these technologies have shown promising results in clinical trials.
LINKS:
Review articles:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10718186/pdf/nihms-1949762.pdf
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4444397/pdf/nihms-663143.pdf
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8486303/pdf/nihms-1729966.pdf
Brain Ponderings podcast with Mark Mattson